Authored date:2006-03-09

Patient History

Patient 1:
30-year-old female patient with visual disturbances, swallowing difficulty, fine motor disturbances and paraesthesia of the right hand and of the abdominal skin. The diagnosis of multiple sclerosis (MS) was established in 1992.

Image Findings

The subcortical lesion which is detected on the Dark Fluid SPACE image (3D FLAIR) image can not be seen in the 2D FLAIR image (Figure 1 and 1A). Figure 2 and 2A illustrate that a subcortical lesion can be delineated much better on the SPACE (3D FLAIR) than on the 2D FLAIR sequence image. In Figure 3 and 3A one temporal lesion is not clearly visualized on the 2D FLAIR image, but on the SPACE (3D FLAIR) image it is identified as a lesion.

Fig. 1-3  2D FLAIR, TR: 10,000 ms, TE: 97 ms, TI: 2,500 ms, slice thickness: 5 mm, FOV: 220.

Fig. 1A-3A  Dark Fluid SPACE (3D FLAIR), TR: 6000, TE: 353, TI: 2200, slice thickness: 1.1 mm, FoV 250.

Patient 2:
52-year-old female patient with visual disturbances. MS was diagnosed in 1970.

Fig. 4  2D FLAIR, TR: 10,000 ms, TE: 97 ms, TI: 2,500 ms, slice thickness: 5 mm, FOV: 220.

Fig. 4A-4B  Dark Fluid SPACE (3D FLAIR), TR: 6000, TE: 353, TI: 2200, slice thickness: 1.1 mm, FOV 250.